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Research & Programs

CAST has a vigorous research and development program. Details on all our key research programs are below.

Miniaturizing Oxygen Sensor Technology for Tissue Engineering Applications

Understanding the mechanisms underlying cell response to cues from their biomaterial microenvironment will ultimately lead to improved methods to control cell behavior in tissue replacement therapies.

Surface Plasmon-coupled Fluorescence

We are developing a set of methods and devices that are based on surface plasmon-coupled fluorescence are being developed.

Alcohol Sensor

We are developing a steam sterilizable alcohol sensor.

Wireless Sensor Networks for Environmental Applications

We are developing a rugged platform for wireless sensor nodes that measure common environmental parameters.

Sensing Chemistries for Environmental Analytes (pH, oxygen, CO2, NH2)

This research is focused on the development of immobilization methods and studying the influence of immobilization on the sensor behavior.

Low Cost Instrumentation for Biotechnology

We have developed a low-cost, relatively simple analytic apparatus for measuring various analytes of a sample that does not require recalibration and constant upgrades in parts
and equipment.

Sensor for Near Real-time Evaluation of Chemotherapy in Cancer

This project is in collaboration with the UM Greenbaum Cancer Center and Guided Therapeutics, Inc. (formerly Spectrx, Inc.) of Atlanta, GA. CAST staff will synthesize molecularly imprinted polymers specific for apoptosis (cell-death) markers.

Enterotoxin Sensor

This project is in collaboration with the US Department of Agriculture. The objective is to develop a low-cost device to detect enterotoxins in food.

Low Cost Metabolic Monitor

A one-use, disposable device for use by soldiers in the field is being developed to measure glucose, glutamine and lactate (USAMRMC-funded).

Binding Proteins

These soluble proteins are being converted into optical sensors by mutagenesis and chemical labeling with fluorescent probes.

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